Viruses potential in cancer treatment

Abstract

Viruses have the potential to lead to an anti-cancer immunity. Through slight genetic modification the viruses may induce immunogenic cell death. The purpose of this study is to determine the ability of three viruses ability to induce immunogenic cell death. These viruses include Semliki Forest virus (SFV), Adenovirus (Ad), and Vaccinia virus (VV). By studying the mechanisms and pathways each of these elicit, we gain more insight for how to design and target tumor cells for better design of viruses for therapy.