Targeted lipid nanoparticles with CRISPR-Cas9 gene editing for cancer therapy

Abstract

Since its discovery more than a decade ago, CRISPR has evolved into a verb as well as an acronym, revolutionizing biomedical research and opening up new paths for the study of cells in general. When it comes to cancer genetics, the non-coding genome, and tumor heterogeneity in cancer research, CRISPR-associated technologies have opened up previously unsolvable challenges. They have also provided fresh insights on therapeutic vulnerabilities in cancer research. The development of CRISPR systems as a tool for cancer research and the application of these technologies to better cancer detection and treatment are discussed in this article