Emerging Treatments for Metastatic Breast Cancer

Kathryn Hobbs

Abstract


An estimated that 1 in 8 women will be diagnosed with breast cancer in their lifetime and 1 in 3 if those will become metastatic. While many cases of breast cancer can be caught early through breast cancer screening, cases that are diagnosed late or progress into metastatic breast cancer can be fatal. Several recent studies explore treatments that target metastatic breast cancer and aim to have a higher success rate than previous treatment options. One study developed nanoparticles with a formulation that was tolerated better and had higher plasma and tumor AUCs compared to the maximum dose of a commonly used chemotherapy medication2 . Another study aimed to identify abnormalities in patient genomes to provide individualized targeted therapy1 . A third treatment is a combination treatment using antiangiogenesis and immune activation to treat metastatic breast cancer3 . Currently researchers in this field are exploring any opportunity to raise the success rates of treatments for metastatic breast cancer, through new chemotherapies, nanoparticles, and targeted therapies.

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