Sickle cell Anemia

Abstract

The purpose of reviewing sickle cell disease is to identify the classification of this disease and what really are its causes and consequences. Basically, sickle cell disease is one of the most common hereditary anemia that include disorders in the structure or synthesis of hemoglobin and it mainly caused by congenital abnormalities in hemoglobin structure. And as known clinically that hemoglobin is the major part that is responsible to transport oxygen from the lungs to the rest of the body. Thus, due to the changing in the shape of erythrocytes which become crescent in shape and fragile in which this may lead to a hemolytic anemia which causes a destroy of red blood cells by the liver and spleen. Accordingly, this microreveiw will briefly discuss how this occurs and what modern methods are utilized to distinguish this type of inherited disease and what the latest ways to treat and handle this disease.