The Effects of Cefotaxand Imipnemon mRNA Transcription in ATP Synthase Related Genes

Erin Hester, Matthew Cartwright, Dominique Young, Elizabeth Chavarria, Nathanial Torres, William Johnson, Patricia Canaan

Abstract


We researched the bacterium Elizabethkingia anophelis, focusing specifically on a group of genes pertaining to ATP synthase. We used the RAST database to find the genes, and determine the gene sequences. We then used the chart provided to determine if two drugs (Imipenem and Cefotax) had an impact on mRNA transcription. According to the chart, cefotax increased mRNA translation in two of the six genes, and imipenem reduced mRNA translation in four of the six genes. This indicates that imipenem would be a better treatment option for Elizabethkingia anophelis than cefotax.

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