Five Heat Shock Proteins and Their Abundance of Transcriptions in E. anophelisR26 in Three Different Conditions

Abstract

Elizabethkingia anophelis is an antibiotic resistant bacteria causing life threatening disease in people across the United States. In order to understand how it is resisting antibiotic treatment, we selected five heat shock proteins from E. anophelisand compared their number of transcript levels under two different antibiotics: Cefotax and Imipenem.We looked for significant changes in the level of transcripts from the control to each condition. For gene #1326, a significant change of 1.5 occurred when the gene was exposed to Cefotax. Gene #209 had no significant changes in either antibiotic. When exposed to Cefotax, gene #223 significantly changed by -3.5. When exposed to Imipenem, gene #223 significantly changed by 1.6. Gene #2968 significantly changed by -2.0 when exposed to Cefotax and by 2.5 when exposed to Imipenem. Gene #1796, when exposed to Cefotax, significantly changed by 1.9, and by -1.6 when exposed to Imipenem.