A Review about a New Technique in Genome Editing

Abstract

       Similar to the RNA-guided endonuclease Cas9, the Argonaute protein family can also use oligonucleoti-des as guides to degrade invasive genomes. Recently, some Chinese researchers have developed a new technique for genome editing in human cells, which uses a DNA-guided endonuclease named Natronobacterium gregoryi Argonaute (NgAgo). Compared to CRISPR-Cas9, this technique has many differences and new features. Although this technique is not as mature as CRISPR-Cas9, it has a good prospect according to the research.