Vol 3 (2017)

Undergraduate students from Nanjing University class examine, investigate, and offer analysis of current scientific studies and events.

Table of Contents

Proteins and cellular structures

A Review about a New Technique in Genome Editing
Tao Wang
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Recognition mechanism of Cpf1-crRNA complex in CRISPR-Cpf1 from crystal structure
Tao Liu
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Perspective of chitosan hydrogel
Ke Zhu
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Splicing process under cryo-EM: structure of U4/U6.U5 tri-snRNP
Jiachen Sun
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Mechanism for substrate preference of TET with structural analyses
Yao Zhao
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A magnetic protein biocompass
Junli Ma
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Review of ’Protein folding guides disulfide bond formation’
Junqin Chen
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Interplay among folding, binding, and allostery of proteins
Youyuan Deng
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Structure reconstruction of human γ-secretase
Yunwen Lu
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Enzyme-Instructed Self-Assembly of Small d-Peptides as a Multiple-Step Process for Selectively Killing Cancer Cells
Yifan Xu
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Regulation

Protein Activity Regulation Based on Proximity Hybridization
Yizhuo Yang
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The novel CRISPR-dCas9 based DNA demethylation system
Jiang Zhang
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Health

Selectively Developmental Synapse Elimination
Yiyang Chen
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Disease

The basic mechanism of pre-mRNA splicing
Yecheng Wang
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The molecular mechanism of CRISPR/Cas9 system and its application in gene therapy of human diseases
Zhen Jin
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Cancer

Tumor-secreted miR-214 delivered on T cells to promote tumor growth
Ying Yu
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Stem cells

single cell technology in tracing haematopoietic stem cell formation
Lingling Hao
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Articles

Optical DNA Sequencing in a Nanopore Array
Shitian Wei
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