Analyzing ATP Synthase Gene Activity in Elizabethkingia anophelis

Abstract

Elizabethkingia anophelis is a gram-negative bacteria that causes blood stream infections in the human body. In this study, databases were used to study genes associated with ATP synthase. Each of the subunits investigated serve a specific function in the ATP synthase reaction. The expression of genes was analyzed under the influence of Cefotax and Imipenem antibiotics in order to determine what specific genes were harmed under antibiotics. It was concluded that ATP synthase gamma chain was expressed heavily under Cefotax and that ATP synthase delta chain was expressed heavily under Imipenem which could indicate a possible disruption to the ATP synthase reaction.